About the Study

If you are taking antiepileptic medications and are still having partial-onset seizures, you may qualify to take part in this clinical research study.

This clinical study is designed to determine if an investigational antiepileptic medication is effective in controlling partial-onset seizures. This is a study of monotherapy use of a study drug, which means that the study drug will be added to your current epilepsy drugs and then the current drugs will be slowly removed. All patients in the study will receive the study drug.

Click here to download the study brochure

Join the national epilepsy research community

If you qualify and decide to join this study, you will take a more active role in your health care, become informed, and help researchers test a new medication to help prevent seizures. This investigational medication may help you and other people with epilepsy in the future.

You will receive study-related care at no cost to you which includes all study visits with medical specialists, all monitoring, seizure tracking, medical tests, and supplies related to this study. The study medication will be provided to you without charge. You can participate even if the study doctor is not part of your health insurance network.

How is this study designed?

If you qualify and decide to take part, you will receive the study drug as there is no placebo for this trial. You will take your study medication once a day.

Why should I participate?

During the study, all will receive, at no cost to them:

  • Study-related care from a medical specialist
  • Study-related exams, tests, and health and seizure monitoring
  • Study medication
  • Compensation for travel, travel arrangements, or lodging for appointments can be provided for qualified participants

You can also learn more about your epilepsy and become more empowered through knowledge:

  • Monitor your seizures and symptoms through an epilepsy diary
  • Learn more about your seizures pattern
  • Become part of the national epilepsy research community

What does the study involve?

If you decide to participate, you must be willing to:

  • Visit the study center 10 times in 22 weeks
  • Have your blood drawn for testing on at least 4 separate occasions
  • Take the study medication every day
  • Keep a daily diary, recording whether or not you have had a seizure

At the end of the study, should you decide, you may also be eligible to take part in an optional 'extension study'. You will continue to be part of this research community and continue to receive the care and oversight from the same team of medical specialists.

Learn more about the study visits.

What happens during the study visits?

The study visits will include:

  • Questions and surveys about your health
  • Review of your diary
  • Physical and neurological exams
  • Tests (blood, urine, ECG*)

For study visits you will need to:

  • Fast (except water) for 8 hours before attending the clinic visits
  • Bring your study medication
  • Bring your epilepsy diary

* An ECG, also called an electrocardiogram or EKG, measures your heart's electrical activity. Sticky patches called electrodes are attached to your arms, legs, and chest with a gel. A machine records your heart's electrical activity for a few minutes.

*For additional information about what the study visits will include, you will be able to speak with study staff prior to agreeing to participate in the study

What are the risks of this study?

A member of the clinical study team will discuss the potential risks and benefits of this study with you, and answer any questions you may have. It is important to know that you will be monitored closely by medical specialists, and during each study visit, the medical staff will check your health and seizure status closely, as well as checking with you about any problems related to the study medication.

Make sure you are fully informed before you agree to participate

If you qualify to take part in this study, members of the study's medical team will discuss the details of this research study. This is called the 'informed consent' process. This helps you understand the key elements of the study including:

  • Study design
  • Study medication
  • Tests you will have
  • What you will be asked to do (daily seizure documentation)
  • Possible risks and benefits of the study medication, examinations, and procedures

It is important that you fully understand what is involved. We recommend you prepare a list of questions to ask the study team when you meet them. To get you started, we have put together a list of suggested questions that you can print out or save to your computer. Click here to open the file.